years old, offered with large lesion involving the mandibular anterior enamel. Radiographic exams together with axial and coronal computed tomography scans confirmed a radiolucent space with multilocular side suggesting differential analysis of ameloblastoma, aneurismal bone cyst, fibrous dysplasia and big cells lesion. Biopsy was made and the presence of multinucleated large cells and groups of collagen fibers with areas of extravasation of erythrocytes and hemosiderin deposit was detected under mild microscopy. For a definitive diagnosis, biochemical checks were made in the blood for dedication of the levels of alkaline
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