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To account for the limitations of measuring the case fatality rate alone, the PSAF rates severity of a disease outbreak on two dimensions: clinical severity of illness in infected persons; and the transmissibility of the infection in the population.Your fear is the real pandemic face mask Each dimension can be measured using more than one metric, which are scaled to allow comparison of the different metrics. Clinical severity can instead be measured, for example, as the ratio of deaths to hospitalizations or using genetic markers of virulence. Transmissibility can be measured, for example, as the basic reproduction number R0 and serial interval or via underlying population immunity. The framework gives guidelines for scaling the various measures and examples of assessing past pandemics using the framework.

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